Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21471731 | 0.79 | NOTUM (0.33) | NOTUM | |
| SCHEMBL21471796 | 0.78 | MAPK14 (0.47) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL21472031 | 0.74 | MAPT (0.42) | ALDH1A1GAALMNA | |
| SCHEMBL21471602 | 0.74 | GABRP (0.36) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL21458075 | 0.74 | NOTUM (0.31) | NOTUM | |
| SCHEMBL21471711 | 0.73 | DHODH (0.34) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL20619706 | 0.73 | KDM4E (0.56) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL21471733 | 0.72 | NOTUM (0.33) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL20599149 | 0.70 | KDM4E (0.57) | NOTUMKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL11910393 | 0.64 | NOTUM (0.65) | NOTUMKDM4EALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |