SCHEMBL21471646

SCHEMBL21471646

C=CS/C(=C\C)CSC(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.49
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
SLC6A4 P31645 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8213237 0.72 SLC6A3 (0.55) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1121660 0.69 SLC6A3 (0.66) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2577670 0.69 SLC6A3 (0.65) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL2577794 0.67 SLC6A3 (0.62) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL16012005 0.67 SLC6A3 (0.60) SLC6A3
SCHEMBL1537233 0.66 SLC6A3 (0.61) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL2577789 0.66 SLC6A3 (0.61) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17504057 0.66 SLC6A3 (0.52) SLC6A3CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL21472920 0.66 SLC6A3 (0.35) SLC6A3
SCHEMBL5022083 0.66 SLC6A3 (0.65) SLC6A3CYP1A2CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553053-A1 (S)-ENANTIOMERIC FORM OF A HETEROCYCLIC COMPOUND HAVING MOTIVATION IMPROVING AND/OR REFERENCE MEMORY ENHANCING ACTIVITY Red Bull GmbH (AT) 2019-10-16 EP disclosed