Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290437 | 0.84 | ALDH1A1 (0.51) | SLC6A3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5273905 | 0.83 | SLC6A3 (0.57) | SLC6A3ALDH1A1KMT2ARXFP1 | |
| SCHEMBL11641195 | 0.83 | SLC6A3 (0.53) | SLC6A3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1121660 | 0.79 | SLC6A3 (0.66) | SLC6A3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15265480 | 0.79 | ALDH1A1 (0.47) | SLC6A3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2577670 | 0.79 | SLC6A3 (0.65) | SLC6A3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13982744 | 0.79 | SLC6A3 (1.00) | SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL2577794 | 0.77 | SLC6A3 (0.62) | SLC6A3ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22446781 | 0.77 | SLC6A3 (0.50) | SLC6A3 | |
| SCHEMBL32689546 | 0.77 | PDPK1 (0.59) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10710061-B2 | Ion pair catalysis of tungstate and molybdate | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-07-14 | — | — | US | disclosed |
| US-10710061-B2 | Ion pair catalysis of tungstate and molybdate | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-07-14 | — | — | US | disclosed |
| US-20190105646-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2019-04-11 | — | — | US | disclosed |
| US-20190105646-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2019-04-11 | — | — | US | disclosed |
| US-20180195053-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF ARMODAFINIL | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-07-12 | — | — | US | disclosed |
| US-20180037872-A1 | BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF ARMODAFINIL | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2018-02-08 | — | — | US | disclosed |
| WO-2017164813-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017164813-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2017-09-28 | — | — | WO | disclosed |
| US-8759583-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2014-06-24 | — | — | US | disclosed |
| US-8759583-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | TEVA SANTE (FR) | 2014-06-24 | — | — | US | disclosed |
| US-7317126-B2 | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation | CEPHALON FRANCE (FR) | 2008-01-08 | — | — | US | disclosed |
| EP-1663963-B1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2007-06-27 | — | — | EP | disclosed |
| US-7235691-B2 | Crystalline forms of modafinil | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-06-26 | — | — | US | disclosed |
| US-7211684-B2 | Method for preparing methyl 2-diphenylmethylsulfinylacetate | CEPHALON FRANCE (FR) | 2007-05-01 | — | — | US | disclosed |
| US-7211684-B2 | Method for preparing methyl 2-diphenylmethylsulfinylacetate | CEPHALON FRANCE (FR) | 2007-05-01 | — | — | US | disclosed |
| US-7186860-B2 | Process for the preparation of 2-[(diphenylmethyl) thio] acetamide | ALEMBIC LIMITED (IN) | 2007-03-06 | — | — | US | disclosed |
| EP-1309547-B1 | CRYSTALLINE AND PURE MODAFINIL, AND PROCESS OF PREPARING THE SAME | TEVA PHARMA (IL) | 2007-01-17 | — | — | EP | disclosed |
| US-20060128812-A1 | Process for the preparation of 2-[(diphenylmethyl) thio] acetamide | ALEMBIC LIMITED (IN) | 2006-06-15 | — | — | US | disclosed |
| WO-2005028428-A1 | PROCESS FOR ENANTIOSELECTIVE SYNTHESIS OF SINGLE ENANTIOMERS OF MODAFINIL BY ASYMMETRIC OXIDATION | CEPHALON FRANCE (FR) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004075827-A2 | PROCESS FOR THE PREPARATION OF 2-[(DIPHENYLMETHYL) THIO] ACETAMIDE | ALEMBIC LIMITED (IN) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10710061-B2 | Ion pair catalysis of tungstate and molybdate | PRDX3, PRDX4, PRDX2 | SLC6A3 123/4885ALDH1A1 1230/4885CYP1A2 1800/4885 |
| US-20060128812-A1 | Process for the preparation of 2-[(diphenylmethyl) thio] acetamide | ADH1A, TAAR1, TAAR5 | SLC6A3 149/4885ALDH1A1 121/4885CYP1A2 25/4885 |
| US-20190105646-A1 | ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE | PRDX3, PRDX4, PRDX6 | SLC6A3 103/4885ALDH1A1 1492/4885CYP1A2 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.