Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21472043 | 0.89 | STING1 (0.36) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL21474621 | 0.83 | GAA (0.44) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL21471611 | 0.82 | AVPR2 (0.38) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL20619667 | 0.82 | AVPR2 (0.38) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL20619531 | 0.79 | ALDH1A1 (0.48) | MAPTRAB9AALDH1A1GAALMNA | |
| SCHEMBL21471676 | 0.78 | CHRM2 (0.32) | ALDH1A1GAA | |
| SCHEMBL20620045 | 0.78 | HDAC1 (0.42) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL21474754 | 0.77 | AVPR2 (0.38) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL21471718 | 0.77 | AVPR2 (0.38) | AVPR2CYP11B2MAPTRAB9AALDH1A1 | |
| SCHEMBL21471733 | 0.76 | NOTUM (0.33) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |