Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474754 | 1.00 | AVPR2 (0.38) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL20619667 | 0.83 | AVPR2 (0.38) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL21474621 | 0.83 | GAA (0.44) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL20620045 | 0.81 | HDAC1 (0.42) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL20619531 | 0.80 | ALDH1A1 (0.48) | GAALMNAALDH1A1TP53MAPT | |
| SCHEMBL20622168 | 0.80 | AVPR2 (0.41) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL21471679 | 0.77 | AVPR2 (0.35) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL21471611 | 0.77 | AVPR2 (0.38) | AVPR2AVPR1AHDAC1HDAC6GAA | |
| SCHEMBL21478313 | 0.76 | CHRM2 (0.36) | HDAC6GAALMNAALDH1A1KDM4E | |
| SCHEMBL20599241 | 0.76 | AVPR2 (0.40) | AVPR2AVPR1AHDAC1HDAC6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199908-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |