Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21421874 | 0.82 | GRIN1 (0.32) | MBOAT4GRIN1GRIN2BLNPEP | |
| SCHEMBL20128770 | 0.81 | GRIN1 (0.31) | MBOAT4GRIN1GRIN2B | |
| SCHEMBL21673606 | 0.79 | MBOAT4 (0.34) | MBOAT4GRIN1GRIN2BLNPEP | |
| SCHEMBL24654249 | 0.77 | ACACB (0.33) | — | |
| SCHEMBL20128806 | 0.75 | — | — | |
| SCHEMBL2586308 | 0.75 | LOX (0.47) | MBOAT4GRIN1GRIN2BLNPEP | |
| SCHEMBL2581578 | 0.75 | LOX (0.47) | MBOAT4GRIN1GRIN2BLNPEP | |
| SCHEMBL20128807 | 0.75 | HRH3 (0.37) | GRIN1GRIN2B | |
| SCHEMBL20128779 | 0.74 | GRIN1 (0.32) | GRIN1GRIN2B | |
| SCHEMBL21673536 | 0.74 | LNPEP (0.30) | LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161841-B2 | Modulators of proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20190315732-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315732-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | MDM2, CRBN, VHL | MBOAT4 4299/4885GRIN1 2783/4885GRIN2B 3367/4885 |
| US-11161841-B2 | Modulators of proteolysis and associated methods of use | MDM2, CRBN, VHL | MBOAT4 4299/4885GRIN1 2783/4885GRIN2B 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.