Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | POLD1 | P28340 | 1/20 | 0.44 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932012 | 0.83 | TK1 (0.63) | TK1POLB | |
| SCHEMBL8711260 | 0.83 | TK1 (0.63) | TK1POLB | |
| SCHEMBL2092764 | 0.83 | TK1 (0.55) | TK1POLB | |
| SCHEMBL291317 | 0.83 | TK1 (0.55) | TK1POLB | |
| SCHEMBL14279195 | 0.82 | TK1 (0.55) | TK1POLBPOLA1POLD1 | |
| SCHEMBL26757239 | 0.82 | TK1 (0.55) | TK1POLBPOLA1POLD1 | |
| SCHEMBL8898158 | 0.82 | TK1 (0.54) | TK1POLB | |
| SCHEMBL8711473 | 0.82 | TK1 (0.54) | TK1POLB | |
| SCHEMBL8896482 | 0.82 | TK1 (0.54) | TK1POLB | |
| SCHEMBL8897744 | 0.81 | TK1 (0.53) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200273-A1 | NOVEL PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-10-17 | — | — | WO | disclosed |