Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711260 | 1.00 | TK1 (0.63) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL21473346 | 0.83 | TK1 (0.57) | TK1POLB | |
| SCHEMBL8897744 | 0.82 | TK1 (0.53) | TK1POLB | |
| SCHEMBL2092764 | 0.81 | TK1 (0.55) | TK1POLB | |
| SCHEMBL291317 | 0.81 | TK1 (0.55) | TK1POLB | |
| SCHEMBL78118 | 0.81 | TK1 (0.53) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL19242604 | 0.81 | TK1 (0.53) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL2011590 | 0.81 | BCHE (0.56) | TK1LMNAALBBLM | |
| SCHEMBL16127042 | 0.81 | BCHE (0.56) | TK1LMNAALBBLM | |
| SCHEMBL8711473 | 0.80 | TK1 (0.54) | TK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501429-B2 | Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-03-10 | — | — | US | disclosed |