Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.57 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378881 | 0.89 | NR4A2 (0.68) | NR4A1NR4A2NR4A3MCL1GSTP1 | |
| SCHEMBL17952637 | 0.88 | NR4A2 (0.71) | NR4A1NR4A2NR4A3PPARGPPARD | |
| SCHEMBL16320242 | 0.85 | NR4A2 (0.71) | NR4A1NR4A2NR4A3PPARGPPARD | |
| SCHEMBL228290 | 0.84 | NR4A2 (0.74) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL1795022 | 0.83 | MEN1 (0.75) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL26574732 | 0.83 | MEN1 (0.70) | NR4A1NR4A2NR4A3MAOBPARP10 | |
| SCHEMBL16351983 | 0.82 | NR4A2 (0.61) | NR4A1NR4A2NR4A3PPARGPPARD | |
| SCHEMBL18500372 | 0.81 | NR4A2 (0.65) | NR4A1NR4A2NR4A3MCL1GSTP1 | |
| SCHEMBL17072095 | 0.81 | LMNA (0.67) | NR4A1NR4A2NR4A3PPARGPPARD | |
| Bicarbonate SCHEMBL9638235 | 0.81 | FFAR1 (0.71) | NR4A1NR4A2NR4A3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3149109-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |