Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952637 | 0.93 | NR4A2 (0.71) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL16320242 | 0.90 | NR4A2 (0.71) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL18500372 | 0.86 | NR4A2 (0.65) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL17081101 | 0.86 | LMNA (0.57) | MCL1FFAR1MAOBDHODHPPARG | |
| SCHEMBL3564078 | 0.85 | MRGPRX4 (0.72) | NR4A2FFAR1TP53PKMNFKB1 | |
| SCHEMBL1756453 | 0.84 | RXRA (0.69) | NR4A2NR4A1NR4A3SRD5A2MAOB | |
| SCHEMBL19133762 | 0.84 | NR4A2 (0.58) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL10128671 | 0.84 | LMNA (0.60) | NR4A2NR4A1NR4A3FFAR1MAOB | |
| SCHEMBL16351981 | 0.83 | FFAR1 (0.51) | NR4A2NR4A1NR4A3MEN1KMT2A | |
| SCHEMBL4949143 | 0.82 | NR4A2 (0.90) | NR4A2NR4A1NR4A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |