Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14798043 | 0.89 | S1PR1 (0.38) | S1PR1PPARDPPARG | |
| SCHEMBL15021688 | 0.86 | S1PR1 (0.43) | S1PR1PPARDPPARGADORA2AALDH1A1 | |
| SCHEMBL2146380 | 0.85 | S1PR1 (0.40) | S1PR1PPARDPPARG | |
| SCHEMBL2146693 | 0.82 | S1PR1 (0.48) | S1PR1PPARDPPARGALDH1A1LMNA | |
| SCHEMBL14797142 | 0.81 | S1PR1 (0.53) | S1PR1PPARDPPARGADORA2AALDH1A1 | |
| SCHEMBL2146740 | 0.80 | S1PR1 (0.47) | S1PR1PPARDPPARGALDH1A1LMNA | |
| SCHEMBL15021666 | 0.79 | S1PR1 (0.42) | S1PR1PPARDPPARG | |
| SCHEMBL14798762 | 0.77 | S1PR1 (0.44) | S1PR1PPARDPPARG | |
| SCHEMBL14798206 | 0.77 | S1PR1 (0.44) | S1PR1PPARDPPARG | |
| SCHEMBL14798724 | 0.77 | S1PR1 (0.44) | S1PR1PPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748436-B2 | Carboxylic acid derivatives having a 2,5,7-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-06-10 | — | — | US | disclosed |
| EP-2523958-B1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-12-25 | — | — | EP | disclosed |
| US-20130079357-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2013-03-28 | — | — | US | disclosed |
| EP-2523958-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086077-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079357-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5,7-SUBSTITUTED OXAZOLOPYRIMIDINE RING | DPYD, OXGR1, ALDH1A1 | S1PR1 2137/4885PPARD 878/4885PPARG 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.