Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | XIAP | P98170 | 1/20 | 0.63 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SDCBP | O00560 | 1/20 | 0.52 |
| ▸ | SDC2 | P34741 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585291 | 1.00 | ALOX15 (0.63) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2025656 | 0.88 | KMT2A (0.61) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL31667158 | 0.88 | NPC1 (0.54) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2023868 | 0.88 | KMT2A (0.61) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2025654 | 0.88 | KMT2A (0.61) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2025776 | 0.87 | ALOX15 (0.53) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL2026146 | 0.87 | MEN1 (0.52) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL23424756 | 0.85 | ALOX15 (0.61) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL120182 | 0.82 | ALOX15 (0.57) | ALOX15KDM4EALDH1A1TSHRXIAP | |
| SCHEMBL21929812 | 0.82 | SDCBP (0.54) | ALOX15KDM4EALDH1A1TSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196938-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | 华东理工大学 | 2019-10-17 | — | — | WO | disclosed |