Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473598 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL20578654 | 0.76 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL21473602 | 0.75 | PRMT3 (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL24861985 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL10160275 | 0.74 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL22997178 | 0.71 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL22962736 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL14459671 | 0.68 | PIK3CD (0.37) | PIK3CDALDH1A1TSHRTDP1 | |
| SCHEMBL18760983 | 0.68 | ALDH1A1 (0.42) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5442712 | 0.67 | PIK3CD (0.35) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778586-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | East China University of Science and Technology (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019196938-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | 华东理工大学 | 2019-10-17 | — | — | WO | disclosed |