Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22297533 | 0.86 | — | — | |
| SCHEMBL19033680 | 0.85 | NCF1 (0.41) | NCF1 | |
| SCHEMBL19957379 | 0.81 | NCF1 (0.38) | NCF1 | |
| SCHEMBL25630748 | 0.78 | NCF1 (0.35) | NCF1 | |
| SCHEMBL26378542 | 0.76 | — | — | |
| SCHEMBL24737699 | 0.74 | NCF1 (0.33) | NCF1 | |
| SCHEMBL18754210 | 0.74 | NCF1 (0.33) | NCF1 | |
| SCHEMBL20230929 | 0.74 | ALDH1A1 (0.32) | ALDH1A1TSHRTDP1 | |
| SCHEMBL20376459 | 0.74 | NCF1 (0.34) | NCF1 | |
| SCHEMBL17327871 | 0.74 | NCF1 (0.39) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778586-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | East China University of Science and Technology (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019196938-A1 | QUINAZOLINE COMPOUND SERVING AS EGFR TRIPLE MUTATION INHIBITOR AND APPLICATIONS THEREOF | 华东理工大学 | 2019-10-17 | — | — | WO | disclosed |