SCHEMBL21473690

SCHEMBL21473690

C=CCc1ccc(OCc2ccc(-c3ccc(COc4ccc(CC=C)cc4OC)cc3)cc2)c(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
PPARA Q07869 3/20 0.71
PPARG P37231 1/20 0.71
PPARD Q03181 1/20 0.71
MAPT P10636 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
MEN1 O00255 3/20 0.63
KMT2A Q03164 3/20 0.63
LMNA P02545 2/20 0.63
GAA P10253 2/20 0.63
KDM4E B2RXH2 1/20 0.63
HTT P42858 1/20 0.63
NPC1 O15118 4/20 0.60
RAB9A P51151 3/20 0.60
POLB P06746 1/20 0.58
HSP90AA1 P07900 1/20 0.58
PTGS1 P23219 2/20 0.57
ALOX5 P09917 3/20 0.56
CYP3A4 P08684 2/20 0.56
AR P10275 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9721996 0.95 ALDH1A1 (0.77) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL874505 0.90 ALDH1A1 (0.69) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL9615213 0.90 ALDH1A1 (0.69) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL9722118 0.87 ALDH1A1 (0.69) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL8964626 0.85 ALDH1A1 (0.62) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL5802074 0.84 ALDH1A1 (0.78) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL10536910 0.84 ALDH1A1 (0.80) ALDH1A1PPARAPPARGPPARDMAPT
SCHEMBL10731044 0.84 ALDH1A1 (0.69) ALDH1A1PPARAPPARGPPARDMAPT
Methyleugenol SCHEMBL1869396 0.84 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDMAPT
Methyleugenol SCHEMBL113794 0.84 ALDH1A1 (1.00) ALDH1A1PPARAPPARGPPARDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019198606-A1 ALKENYL-GROUP-CONTAINING COMPOUND, CURABLE RESIN COMPOSITION, AND CURED OBJECT OBTAINED THEREFROM 日本化薬株式会社 2019-10-17 WO disclosed