Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | PPARA | Q07869 | 3/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | PPARD | Q03181 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721996 | 0.94 | ALDH1A1 (0.77) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL21473690 | 0.90 | ALDH1A1 (0.71) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL874505 | 0.88 | ALDH1A1 (0.69) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL9722118 | 0.85 | ALDH1A1 (0.69) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL8964626 | 0.84 | ALDH1A1 (0.62) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL5802074 | 0.83 | ALDH1A1 (0.78) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL10536910 | 0.83 | ALDH1A1 (0.80) | ALDH1A1PPARAPPARGPPARDMAPT | |
| SCHEMBL13929729 | 0.82 | ACHE (0.61) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11005043 | 0.82 | HPGD (0.60) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10731044 | 0.82 | ALDH1A1 (0.69) | ALDH1A1PPARAPPARGPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4122681-A | — | — | None | — | — | JP | disclosed |
| JP-H04122681-A | THERMAL RECORDING MATERIAL | OJI PAPER CO LTD | 1992-04-23 | — | — | JP | disclosed |
| US-4946908-A | DAMAGE TOLERANCE, SHEAR STRENGTH, THERMOCRACKING | HERCULES INCORPORATED (US) | 1990-08-07 | — | — | US | disclosed |