Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24699692 | 0.84 | NR1I2 (0.31) | NR1I2CYP2D6 | |
| SCHEMBL19770472 | 0.82 | ALDH1A1 (0.34) | CYP2D6MEN1KMT2A | |
| SCHEMBL14339342 | 0.80 | MEN1 (0.36) | NR1I2CYP2D6MEN1KMT2AKIF11 | |
| SCHEMBL12856442 | 0.80 | MEN1 (0.36) | NR1I2CYP2D6MEN1KMT2AKIF11 | |
| SCHEMBL11427912 | 0.79 | CYP2D6 (0.35) | CYP2D6MEN1KMT2APOLBGAA | |
| SCHEMBL13948921 | 0.79 | MEN1 (0.35) | NR1I2CYP2D6MEN1KMT2AKIF11 | |
| SCHEMBL21473768 | 0.79 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL13304254 | 0.78 | CYP2D6 (0.33) | CYP2D6KIF11 | |
| SCHEMBL19770513 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL12292337 | 0.75 | NPC1 (0.32) | CYP2D6MEN1KMT2AKIF11RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | NR1I2 3479/4885CYP2D6 1066/4885MEN1 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.