SCHEMBL12856442

SCHEMBL12856442

CC(C)(C)c1ccc(N(c2ccccc2)c2ccc3ccc4c(N(c5ccccc5)c5ccc(C(C)(C)C)cc5)ccc5ccc2c3c54)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
CYP2D6 P10635 3/20 0.34
NR1H4 Q96RI1 2/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
NR1I2 O75469 1/20 0.32
LMNA P02545 1/20 0.32
ADRA2A P08913 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32
SLC6A4 P31645 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339342 1.00 MEN1 (0.36) MEN1KMT2ARAB9ANPSR1TP53
SCHEMBL13948921 0.98 MEN1 (0.35) MEN1KMT2ARAB9ANPSR1TP53
SCHEMBL12856477 0.94 TSHR (0.34) RAB9ATP53SMN1; SMN2NR1H4LMNA
SCHEMBL19784927 0.93 TSHR (0.42) MEN1KMT2ARAB9ANPSR1TP53
SCHEMBL13304296 0.93 TP53 (0.39) TP53SMN1; SMN2KEAP1NFE2L2NR1H4
SCHEMBL13948908 0.92 TSHR (0.33) NR1H4LMNATSHR
SCHEMBL19660696 0.92 MEN1 (0.32) MEN1KMT2ARAB9ANPSR1TP53
SCHEMBL24425458 0.91 ALDH1A1 (0.37) CYP2D6MAPTTDP1L3MBTL1KDM4E
SCHEMBL20403525 0.91 KEAP1 (0.38) MEN1KMT2ARAB9ANPSR1TP53
SCHEMBL19766158 0.89 DHODH (0.33) MEN1KMT2ARAB9ANPSR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
CN-113906036-B Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-10-25 CN disclosed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-11839138-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 US disclosed
US-11839138-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG DISPLAY CO., LTD. (KR) 2010-06-24 US disclosed
US-7700201-B2 Organic electroluminescent device LG DISPLAY CO., LTD. (KR) 2010-04-20 US disclosed
US-20080001123-A1 Luminescent Ink Composition for Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD (JP) 2008-01-03 US disclosed
US-20080001123-A1 Luminescent Ink Composition for Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD (JP) 2008-01-03 US disclosed
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-12-20 US disclosed
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-12-20 US disclosed
EP-1790631-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC MEN1 2135/4885KMT2A 466/4885RAB9A 3457/4885
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA MEN1 734/4885KMT2A 2378/4885RAB9A 3193/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 MEN1 3441/4885KMT2A 723/4885RAB9A 3989/4885
US-20100155714-A1 ORGANIC ELECTROLUMINESCENT DEVICE L1CAM, AOC2, AOC1 MEN1 2740/4885KMT2A 1177/4885RAB9A 1638/4885
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 MEN1 2300/4885KMT2A 922/4885RAB9A 2346/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 MEN1 3441/4885KMT2A 723/4885RAB9A 3989/4885
US-20070292714-A1 Aromatic Amine Derivative and Organic Electroluminescent Device Using Same TYR, DDC, PNMT MEN1 3675/4885KMT2A 822/4885RAB9A 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.