Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473905 | 0.91 | TNKS (0.33) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL21473904 | 0.90 | TNKS (0.32) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL21473773 | 0.87 | NPSR1 (0.31) | — | |
| SCHEMBL25824103 | 0.83 | SIGMAR1 (0.34) | SIGMAR1TDP1L3MBTL1 | |
| SCHEMBL4079852 | 0.82 | TNKS (0.35) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL13171185 | 0.82 | TNKS (0.35) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL4079155 | 0.81 | ALOX5 (0.31) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL4089242 | 0.81 | TNKS (0.32) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL16216633 | 0.81 | SIGMAR1 (0.33) | TNKSPARP1TNKS2HDAC6PARP2 | |
| SCHEMBL21475608 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | TNKS 4302/4885PARP1 2419/4885TNKS2 4273/4885 |
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | TNKS 4302/4885PARP1 2419/4885TNKS2 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.