SCHEMBL2147449

SCHEMBL2147449

CCCCC(CC)[C]1C(=O)c2ccccc2C1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
PTPN1 P18031 2/20 0.42
APAF1 O14727 1/20 0.42
SOAT1 P35610 10/20 0.41
S100A4 P26447 1/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MITF O75030 2/20 0.41
NR1I2 O75469 1/20 0.41
PKM P14618 1/20 0.41
RECQL P46063 1/20 0.41
CDC25B P30305 1/20 0.39
ALDH2 P05091 1/20 0.39
ALDH3A1 P30838 1/20 0.39
GAA P10253 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6089749 0.93 NR1I2 (0.49) ALDH1A1PTPN1SOAT1NPC1RAB9A
SCHEMBL6088907 0.89 CDC25B (0.42) ALDH1A1PTPN1APAF1SOAT1S100A4
SCHEMBL6088794 0.85 PTPN1 (0.50) ALDH1A1PTPN1SOAT1NPC1RAB9A
SCHEMBL6090734 0.84 CDC25B (0.50) ALDH1A1APAF1SOAT1S100A4NPC1
SCHEMBL6089158 0.79 ALDH1A1 (0.44) ALDH1A1PTPN1APAF1SOAT1S100A4
Anthraquinone SCHEMBL27601272 0.75 MEN1 (0.63) ALDH1A1PTPN1APAF1SOAT1S100A4
Anthraquinone SCHEMBL27605254 0.73 PTPN1 (0.61) ALDH1A1PTPN1APAF1SOAT1S100A4
SCHEMBL6089567 0.73 PTPN1 (0.49) ALDH1A1PTPN1APAF1SOAT1S100A4
SCHEMBL11488767 0.73 CASP3 (0.41) ALDH1A1APAF1SOAT1S100A4NPC1
SCHEMBL598619 0.72 NR1I2 (0.49) ALDH1A1MAPTNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050203230-A1 Flame-retardant polyvinyl chloride compositions TEKNOR APEX COMPANY 2005-09-15 US claimed
US-20050019214-A1 Colorable polymeric particles with biological probes EASTMAN KODAK COMPANY 2005-01-27 US claimed
WO-2004058865-A2 FLAME-RETARDANT POLYVINYL CHLORIDE COMPOSITIONS TEKNOR APEX COMPANY (US) 2004-07-15 WO claimed
US-20040122149-A1 Flame-retardant polyvinyl chloride compositions TEKNOR APEX COMPANY 2004-06-24 US claimed
US-6143484-A ADDING TO EMULSION CONTAINING SILVER HALIDE PARTICLES SUFFICIENT AMOUNT OF SURFACTANT TO PASSIFY SURFACES OF SILVER HALIDE PARTICLES EASTMAN KODAK COMPANY (US) 2000-11-07 US claimed
WO-1999053860-A1 bicycle seat BONYF AG (LI) 1999-10-28 WO claimed
EP-0169236-A1 CONTROLLED RELEASE LIQUID DOSAGE FORMULATIONS FOR PHARMACEUTICALS BATTELLE DEVELOPMENT CORPORATION (US) 1986-01-29 EP claimed
US-4552751-A Long-lasting multi-layered film preparation ONO PHARMACEUTICAL CO., LTD. (JP) 1985-11-12 US claimed
WO-1985003000-A1 CONTROLLED RELEASE LIQUID DOSAGE FORMULATIONS FOR PHARMACEUTICALS BATTELLE DEVELOPMENT CORPORATION (US) 1985-07-18 WO claimed
EP-0050480-A2 Long lasting multi-layered film preparation and process for its production ONO PHARMACEUTICAL CO., LTD. (JP) 1982-04-28 EP claimed
US-4222923-A Adhesive composition and method of use RHODES JOHN 1980-09-16 US claimed
US-20240074968-A1 ORAL PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING PARTICULATE FORMULATION COMPRISING COMPOSITION SUNSHO PHARMACEUTICAL CO LTD (JP) 2024-03-07 US disclosed
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-14 US disclosed
WO-2023147443-A2 NOVEL COMPOSITIONS TULEX PHARMACEUTICALS INC. (US) 2023-08-03 WO disclosed
WO-2023146983-A1 LIQUID RESIN EXTENDED-RELEASE ORAL NALTREXONE FORMULATION FOR TREATING AUTISM-RELATED DISORDERS Aardvark Therapeutics, Inc. (US) 2023-08-03 WO disclosed
US-4076920-A FREE RADICAL CATALYSTS THE B. F. GOODRICH COMPANY (US) 1978-02-28 US disclosed
US-4011388-A PROCESS FOR PREPARING EMULSIONS BY POLYMERIZATION OF AQUEOUS MONOMER-POLYMER DISPERSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-08 US disclosed
US-4002702-A BLENDING A DISPERSION RESIN WITH A NUCLEATING RESIN; SPRAY DRYING STAUFFER CHEMICAL COMPANY (US) 1977-01-11 US disclosed
US-3953386-A Aqueous emulsions containing homogeneous particles of cellulosic ester/acrylic polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-27 US disclosed
US-3936591-A Nonmetallic-sheathed cable THE ANACONDA COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398096-A1 COMPOSITION COMPRISING TETRACYCLIC COMPOUND ALK, ALPI, TTR ALDH1A1 308/4885PTPN1 610/4885APAF1 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.