Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474683 | 0.93 | MAOB (0.40) | SLC6A3MEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL21478273 | 0.84 | SLC6A3 (0.42) | SLC6A3MAPK1 | |
| SCHEMBL21478254 | 0.83 | MAOB (0.39) | ACHESLC6A3MEN1KMT2ALTB4R | |
| SCHEMBL21478276 | 0.75 | FFAR1 (0.39) | SLC6A3LTB4RLTB4R2MAOB | |
| SCHEMBL21478277 | 0.73 | CYP26A1 (0.39) | LTB4RLTB4R2 | |
| SCHEMBL21478274 | 0.68 | SLC6A3 (0.39) | SLC6A3MEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL21474594 | 0.67 | LTA4H (0.41) | MEN1KMT2A | |
| SCHEMBL21474580 | 0.66 | SLC6A3 (0.44) | SLC6A3MEN1KMT2ARAB9A | |
| SCHEMBL21474595 | 0.65 | TSHR (0.42) | SLC6A3MEN1KMT2ALTB4RLTB4R2 | |
| SCHEMBL15969573 | 0.64 | CYP19A1 (0.42) | MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |