Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 12/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097665 | 0.88 | — | — | |
| SCHEMBL3912015 | 0.88 | — | — | |
| SCHEMBL2408337 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL2712999 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL2713002 | 0.85 | — | — | |
| SCHEMBL15190184 | 0.79 | DPP4 (0.46) | EPHX1ALOX5DPP4DPP7DPP8 | |
| SCHEMBL15190112 | 0.78 | EPHX1 (0.58) | EPHX1DPP4DPP7DPP8DPP9 | |
| SCHEMBL8089041 | 0.78 | — | — | |
| SCHEMBL8088500 | 0.78 | EPHX1 (0.58) | EPHX1DPP4DPP7DPP8DPP9 | |
| SCHEMBL15189800 | 0.77 | ALOX5 (0.38) | EPHX1ALOX5DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196780-A1 | NOVEL INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 信达生物制药(苏州)有限公司 | 2019-10-17 | — | — | WO | disclosed |