⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408337 | 1.00 | — | — | |
| SCHEMBL3912015 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2713002 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2712999 | 0.97 | — | — | |
| SCHEMBL15190184 | 0.90 | DPP4 (0.46) | — | |
| SCHEMBL8089041 | 0.89 | — | — | |
| SCHEMBL8088500 | 0.89 | EPHX1 (0.58) | — | |
| SCHEMBL15190112 | 0.89 | EPHX1 (0.58) | — | |
| SCHEMBL21476071 | 0.88 | EPHX1 (0.37) | — | |
| SCHEMBL15189800 | 0.88 | ALOX5 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718280-A2 | Derivatives of beta-aminopropionic acid with a fungicidal activity | ISAGRO RICERCA S.r.l. (IT) | 1996-06-26 | — | — | EP | claimed |
| US-20250326745-A1 | BENZOXAZEPIN OXAZOLIDINONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| CN-111909173-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112047960-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-112062778-B | Benzoxazepine oxazolidinone compounds and methods of use thereof | 豪夫迈·罗氏有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-20230000996-A1 | RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2023-01-05 | — | — | US | disclosed |
| EP-2486011-B1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| WO-2015161830-A1 | HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-10-29 | — | — | WO | disclosed |
| CN-102656145-A | Modulators of G-protein coupled receptor 88 | BRISTOL MYERS SQUIBB CO | 2012-09-05 | — | — | CN | disclosed |
| US-7300934-B2 | Benzamide nitriles | ROCHE PALO ALTO LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300934-B2 | Benzamide nitriles | ROCHE PALO ALTO LLC (US) | 2007-11-27 | — | — | US | disclosed |
| WO-2004106285-A1 | BENZAMIDE NITRILE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-09 | — | — | WO | disclosed |
| EP-0843967-B1 | Use of Beta-aminopropionic acid derivatives as fungicides | ISAGRO RICERCA SRL (IT) | 2000-04-05 | — | — | EP | disclosed |
| US-5856311-A | Derivatives of β-aminopropionic acid with a fungicidal activity | ISAGRO RICERCA SRL (IT) | 1999-01-05 | — | — | US | disclosed |
| EP-0843967-A1 | Use of Beta-aminopropionic acid derivatives as fungicides | ISAGRO RICERCA S.r.l. (IT) | 1998-05-27 | — | — | EP | disclosed |
| EP-0718280-A2 | Derivatives of beta-aminopropionic acid with a fungicidal activity | ISAGRO RICERCA S.r.l. (IT) | 1996-06-26 | — | — | EP | disclosed |