Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LIPA | P38571 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719576 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| Bicarbonate SCHEMBL679005 | 0.91 | MAPT (0.44) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| Bicarbonate SCHEMBL35810 | 0.91 | MAPT (0.44) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| Bicarbonate SCHEMBL2763274 | 0.91 | MAPT (0.44) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| SCHEMBL4552150 | 0.78 | MAPT (0.39) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| SCHEMBL6382164 | 0.78 | MAPT (0.39) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| SCHEMBL5615220 | 0.76 | EPHX1 (0.42) | MAPTMEN1KMT2AHTTAPOBEC3A | |
| SCHEMBL14271879 | 0.76 | — | — | |
| SCHEMBL22797 | 0.76 | — | — | |
| SCHEMBL5270433 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150590-B1 | S1P MODULATING AGENTS | BIOGEN MA INC (US) | 2019-10-16 | — | — | EP | disclosed |