Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911954 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1HTT | |
| SCHEMBL11329643 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1HTT | |
| SCHEMBL2915127 | 0.93 | — | — | |
| SCHEMBL11904134 | 0.93 | — | — | |
| SCHEMBL12806026 | 0.93 | — | — | |
| SCHEMBL14922899 | 0.85 | — | — | |
| SCHEMBL6083462 | 0.85 | — | — | |
| SCHEMBL1300087 | 0.80 | CYP2C9 (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL8488915 | 0.80 | CYP2C9 (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL11434843 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150590-B1 | S1P MODULATING AGENTS | BIOGEN MA INC (US) | 2019-10-16 | — | — | EP | disclosed |