SCHEMBL2911954

SCHEMBL2911954

CC[C@H]1CC[C@H](C=O)CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21476640 1.00 ALDH1A1 (0.33) ALDH1A1MAPK1TDP1HTT
SCHEMBL11329643 1.00 ALDH1A1 (0.33) ALDH1A1MAPK1TDP1HTT
SCHEMBL2915127 0.93
SCHEMBL11904134 0.93
SCHEMBL12806026 0.93
SCHEMBL14922899 0.85
SCHEMBL6083462 0.85
SCHEMBL1300087 0.80 CYP2C9 (0.36) ALDH1A1MAPK1
SCHEMBL8488915 0.80 CYP2C9 (0.36) ALDH1A1MAPK1
SCHEMBL11434843 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-103254902-B Fluorine-containing liquid crystal compound containing ethane bridged bond and -CF2O- bridged bond XIAN MODERN CHEMISTRY RES INST 2015-02-11 CN disclosed
CN-103242133-B Synthesis method of 4-[2-(trans-4-alkylcyclohexyl)ethyl] bromobenzene XIAN MODERN CHEMISTRY RES INST 2015-02-11 CN disclosed
CN-103145525-B Synthesis method of 1 - fluoro - 3 - [2 - (trans- 4 - alkyl cyclohexyl) ethyl] benzene XIAN MODERN CHEMISTRY RES INST 2015-02-11 CN disclosed
CN-103242854-B Fluorine-containing liquid crystal compound XI'AN INST. OF MODERN CHEMISTRY (CN) 2014-10-15 CN disclosed
CN-103146393-B 3,4,5-trifluoro-biphenyl liquid crystal compound with ethylene XIAN MODERN CHEMISTRY RES INST 2014-07-16 CN disclosed
CN-103254902-A Fluorine-containing liquid crystal compound containing ethane bridged bond and -CF2O- bridged bond XIAN MODERN CHEMISTRY RES INST 2013-08-21 CN disclosed
CN-103242854-A Fluorine-containing liquid crystal compound XIAN MODERN CHEMISTRY RES INST 2013-08-14 CN disclosed
CN-103242133-A Synthesis method of 4-[2-(trans-4-alkylcyclohexyl)ethyl] bromobenzene XIAN MODERN CHEMISTRY RES INST 2013-08-14 CN disclosed
CN-103145525-A Synthesis method of 1 - fluoro - 3 - [2 - (trans- 4 - alkyl cyclohexyl) ethyl] benzene XIAN MODERN CHEMISTRY RES INST 2013-06-12 CN disclosed
CN-103146393-A 3,4,5-trifluoro-biphenyl liquid crystal compound with ethylene XIAN MODERN CHEMISTRY RES INST 2013-06-12 CN disclosed
CN-103131425-A Fluorine-containing liquid crystal compound XIAN MODERN CHEMISTRY RES INST 2013-06-05 CN disclosed
EP-2277858-A1 AMIDE COMPOUND Astellas Pharma Inc. (JP) 2011-01-26 EP disclosed
EP-1640433-B1 CHROMAN DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE COMPOUND DAINIPPON INK & CHEMICALS (JP) 2010-08-25 EP disclosed
US-7226644-B2 Chroman derivative and liquid-crystal composition containing the compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-05 US disclosed
US-20060163536-A1 Chroman dervative and liquid-crystal composition containing the compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-07-27 US disclosed
EP-1640433-A1 CHROMAN DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE COMPOUND Dainippon Ink and Chemicals, Incorporated (JP) 2006-03-29 EP disclosed