Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20233787 | 0.84 | ACACB (0.37) | ACACBEGLN1 | |
| SCHEMBL20128772 | 0.71 | ACACB (0.35) | ACACBEGLN1 | |
| SCHEMBL20324981 | 0.69 | ACACB (0.37) | ACACB | |
| SCHEMBL26627828 | 0.66 | HRH3 (0.57) | — | |
| SCHEMBL21026317 | 0.64 | ACACB (0.35) | ACACB | |
| SCHEMBL20442734 | 0.64 | NQO1 (0.52) | ACACB | |
| SCHEMBL6446075 | 0.63 | FFAR1 (0.50) | — | |
| SCHEMBL26627873 | 0.63 | LTA4H (0.40) | — | |
| SCHEMBL3634841 | 0.62 | HTT (0.58) | EGLN1 | |
| SCHEMBL27097455 | 0.62 | GRM5 (0.36) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020221-A1 | MODULATORS OF TYK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |