Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921840 | 1.00 | ALDH1A1 (0.40) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24921932 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24921936 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24921941 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24922741 | 0.95 | ALDH1A1 (0.38) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24920945 | 0.93 | ALDH1A1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL21477084 | 0.93 | HTR1B (0.38) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL19606317 | 0.93 | EPHX1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24921949 | 0.93 | EPHX1 (0.39) | ALDH1A1GAAHTR1BTSHREPHX1 | |
| SCHEMBL24921951 | 0.91 | EPHX1 (0.37) | ALDH1A1GAAHTR1BTSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332145-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2021057872-A1 | PROTAC SMALL MOLECULE COMPOUND AND APPLICATION THEREOF | 珠海宇繁生物科技有限责任公司 | 2021-04-01 | — | — | WO | disclosed |
| EP-3302572-B1 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS INC (US) | 2021-01-06 | — | — | EP | disclosed |
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230332145-A1 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | EFTUD2, DDX21, SNRPE | ALDH1A1 4159/4885GAA 2888/4885HTR1B 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.