Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230942 | 0.91 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHRH2 | |
| SCHEMBL22851654 | 0.91 | GNAI3 (0.47) | GNAI3GNAO1GNAI1LTA4HHRH2 | |
| SCHEMBL29343604 | 0.84 | HRH2 (0.34) | LTA4HHRH2HRH1HRH3HTT | |
| SCHEMBL6553947 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1LTA4HTHRB | |
| SCHEMBL20328705 | 0.83 | ALDH1A1 (0.42) | HRH3MEN1KMT2A | |
| SCHEMBL21421563 | 0.82 | GNAI3 (0.48) | GNAI3GNAO1GNAI1LTA4H | |
| Bromide SCHEMBL28255534 | 0.82 | GNAI3 (0.52) | GNAI3GNAO1GNAI1LTA4HTHRB | |
| SCHEMBL22520691 | 0.81 | KDM4E (0.40) | GNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL29323634 | 0.81 | HRH1 (0.36) | HRH2HRH1HRH3MEN1KMT2A | |
| SCHEMBL26744659 | 0.81 | HRH2 (0.36) | HRH2HRH1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097251-A1 | OLIGONUCLEOTIDE-CONTAINING TRANSCRIPTION FACTOR TARGETING CHIMERAS | YALE UNIVERSITY (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2019199816-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. (US) | 2019-10-17 | — | — | WO | disclosed |