SCHEMBL21477593

SCHEMBL21477593

CC(=O)c1cnc(C(=O)I)cn1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 2/20 0.44
ALDH1A1 P00352 4/20 0.40
SIRT6 Q8N6T7 2/20 0.39
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
GAA P10253 1/20 0.33
USP7 Q93009 1/20 0.32
MAPK1 P28482 1/20 0.31
P4HA1 P13674 1/20 0.31
MIF P14174 1/20 0.31
P4HTM Q9NXG6 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
POLB P06746 1/20 0.31
PTK2 Q05397 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24027361 0.87 SIRT6 (0.46) ALDH1A1SIRT6NPC1RAB9ASMN1; SMN2
SCHEMBL13165465 0.87 KCNJ1 (0.52) KCNJ1ALDH1A1SIRT6SMN1; SMN2MAPK1
SCHEMBL2059001 0.79 SIRT6 (0.63) KCNJ1ALDH1A1SIRT6NPC1RAB9A
SCHEMBL15305157 0.78 KDM4E (0.48) KCNJ1ALDH1A1SIRT6MAPK1P4HA1
SCHEMBL3608095 0.76 KCNJ1 (0.44) KCNJ1ALDH1A1SIRT6MAPK1P4HA1
Hydrochloric Acid SCHEMBL29202159 0.76 KDM4E (0.46) KCNJ1ALDH1A1SIRT6MAPK1P4HA1
SCHEMBL5041030 0.76 SIRT6 (0.59) KCNJ1ALDH1A1SIRT6SMN1; SMN2P4HA1
SCHEMBL21935846 0.76 KCNJ1 (0.44) KCNJ1ALDH1A1NPC1RAB9AMAPK1
SCHEMBL3608091 0.76 KCNJ1 (0.44) KCNJ1ALDH1A1SIRT6MAPK1P4HA1
SCHEMBL29202158 0.76 KCNJ1 (0.44) KCNJ1ALDH1A1SIRT6NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689489-B2 Polyimide-based block copolymer and polyimide-based film comprising the same LG CHEM LTD. (KR) 2020-06-23 US disclosed
US-20200131315-A1 POLYAMIDE-IMIDE RESIN FILM LG CHEM, LTD. (KR) 2020-04-30 US disclosed
US-20190315925-A1 POLYIMIDE-BASED COPOLYMER AND POLYIMIDE-BASED FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2019-10-17 US disclosed