⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104118 | 0.71 | PIK3CD (0.32) | — | |
| SCHEMBL23061698 | 0.69 | TDP1 (0.33) | — | |
| SCHEMBL104329 | 0.69 | — | — | |
| SCHEMBL1133021 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL3162809 | 0.69 | GAA (0.33) | — | |
| SCHEMBL28332797 | 0.67 | — | — | |
| SCHEMBL23606565 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL29013140 | 0.67 | — | — | |
| SCHEMBL29249247 | 0.67 | — | — | |
| SCHEMBL29249255 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072809-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | US | disclosed |
| US-10894949-B2 | Recombinant AAVS having useful transcytosis properties | UNIVERSITY OF MASSACHUSETTS (US) | 2021-01-19 | — | — | US | disclosed |
| WO-2019200161-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | DESIGN THERAPEUTICS INC. (US) | 2019-10-17 | — | — | WO | disclosed |