SCHEMBL104118

SCHEMBL104118

CC(C)NC(C)(C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3162809 0.97 GAA (0.33) PIK3CD
SCHEMBL24135057 0.76 GAA (0.33)
SCHEMBL7967124 0.73 PIK3CD (0.34) PIK3CD
SCHEMBL25055337 0.73 PIK3CD (0.30) PIK3CD
SCHEMBL22511790 0.73 PIK3CD (0.30) PIK3CD
SCHEMBL21478038 0.71
SCHEMBL276455 0.69 PIK3CD (0.35) PIK3CD
SCHEMBL23061698 0.69 TDP1 (0.33)
SCHEMBL104329 0.69
SCHEMBL24860938 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1386908-B1 AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE INST PHARM & TOXICOLOGY AMMS (CN) 2010-03-03 EP claimed
CN-101502502-A Medicament composition for preventing and treating ischemia-reperfusion injury of kidney BEIJING ENHUA PHARMACEUTICAL I (CN) 2009-08-12 CN claimed
US-7560473-B2 Amine derivative with potassium channel regulatory function, its preparation and use INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) 2009-07-14 US claimed
CN-1250518-C Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application INST OF TOXIC MEDICAL MATERIAL (CN) 2006-04-12 CN claimed
CN-1250519-C Amine derivative with K channel regulation function and its preparing process and application INST OF TOXIC MEDICAL MATERIAL (CN) 2006-04-12 CN claimed
CN-1205175-C Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science INST OF TOXICANT AND MEDICAMEN (CN) 2005-06-08 CN claimed
US-20040266822-A1 Amine derivative with potassium channel regulatory function, its preparation and use INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) 2004-12-30 US claimed
EP-1386908-A1 AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) 2004-02-04 EP claimed
CN-1415596-A Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science INST OF TOXICANT AND MEDICAMEN (CN) 2003-05-07 CN claimed
CN-1365966-A Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application INST OF TOXIC MEDICAL MATERIAL (CN) 2002-08-28 CN claimed
CN-1365967-A Amine derivative with K channel regulation function and its preparing process and application INST OF TOXIC MEDICAL MATERIAL (CN) 2002-08-28 CN claimed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-20250205317-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF STROKE THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2025-06-26 US disclosed
WO-2025124483-A1 ORAL DRUG DOSAGE FORM FOR TARGETED DRUG DELIVERY BASED ON TRACKING MARKER AND METHODS OF DESIGN AND USE THEREOF Triastek, Inc. (CN) 2025-06-19 WO disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
US-20040266822-A1 Amine derivative with potassium channel regulatory function, its preparation and use INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) 2004-12-30 US disclosed
EP-1386908-A1 AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) 2004-02-04 EP disclosed
CN-1415596-A Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science INST OF TOXICANT AND MEDICAMEN (CN) 2003-05-07 CN disclosed
CN-1365966-A Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application INST OF TOXIC MEDICAL MATERIAL (CN) 2002-08-28 CN disclosed
CN-1365967-A Amine derivative with K channel regulation function and its preparing process and application INST OF TOXIC MEDICAL MATERIAL (CN) 2002-08-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 PIK3CD 3182/4885
US-20040266822-A1 Amine derivative with potassium channel regulatory function, its preparation and use KCNMA1, KCNA5, KCNA1 PIK3CD 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.