Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18719354 | 0.88 | CYP1A2 (0.40) | LMNACHKACYP1A2CYP2A6MEN1 | |
| SCHEMBL16344198 | 0.82 | PSMB5 (0.42) | PSMB5TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12249552 | 0.82 | CHKA (0.41) | PSMB5TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20210147 | 0.81 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL20210324 | 0.80 | SMN1; SMN2 (0.37) | PSMB5TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21479952 | 0.80 | TAAR1 (0.41) | TAAR1ALDH1A1LMNASMN1; SMN2CHKA | |
| SCHEMBL12249808 | 0.79 | ALDH1A1 (0.48) | TAAR1ALDH1A1LMNASMN1; SMN2CHKA | |
| SCHEMBL21787742 | 0.79 | PSMB5 (0.40) | PSMB5TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19241177 | 0.79 | MEN1 (0.40) | PSMB5ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL6723671 | 0.79 | ALDH1A1 (0.50) | TAAR1ALDH1A1LMNASMN1; SMN2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| EP-3544984-B1 | BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2020-12-23 | — | — | EP | disclosed |
| US-20190315764-A1 | BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315764-A1 | BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | OCIAD1, OCIAD2, AOC1 | PSMB5 4727/4885TAAR1 420/4885ALDH1A1 99/4885 |
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD1, OCIAD2, AOC1 | PSMB5 4727/4885TAAR1 420/4885ALDH1A1 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.