Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20384981 | 0.87 | TSHR (0.41) | CHKASLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL2198610 | 0.87 | TSHR (0.41) | CHKASLC6A2SLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28328614 | 0.83 | TSHR (0.38) | CHKASLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL13367414 | 0.83 | TSHR (0.46) | ALDH1A1SIGMAR1HSD17B1HSD17B2MAPK13 | |
| SCHEMBL20210324 | 0.82 | SMN1; SMN2 (0.37) | TAAR1ALDH1A1KDM4ECHKAHSD17B1 | |
| SCHEMBL20210349 | 0.82 | POLB (0.35) | TAAR1ALDH1A1KDM4ECHKAHSD17B1 | |
| SCHEMBL15306327 | 0.82 | ALDH1A1 (0.38) | TAAR1ALDH1A1KDM4EUSP2 | |
| SCHEMBL19393440 | 0.82 | ALDH1A1 (0.38) | TAAR1ALDH1A1KDM4EUSP2 | |
| SCHEMBL17368989 | 0.82 | ALDH1A1 (0.38) | TAAR1ALDH1A1KDM4EUSP2 | |
| SCHEMBL24774796 | 0.81 | CHKA (0.40) | TAAR1CHKAGSK3BHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
| US-20190315764-A1 | BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315764-A1 | BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | OCIAD1, OCIAD2, AOC1 | TAAR1 420/4885ALDH1A1 99/4885KDM4E 3832/4885 |
| US-11584753-B2 | Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD1, OCIAD2, AOC1 | TAAR1 420/4885ALDH1A1 99/4885KDM4E 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.