Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900165 | 0.90 | TDP1 (0.57) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL12677778 | 0.87 | TDP1 (0.55) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL18355825 | 0.86 | TDP1 (0.50) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL17203007 | 0.86 | MMP8 (0.59) | TDP1MMP8L3MBTL1LMNACSNK1D | |
| SCHEMBL5321935 | 0.82 | TDP1 (0.67) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL7412568 | 0.82 | TDP1 (0.49) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL7429704 | 0.81 | TDP1 (0.61) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL5857539 | 0.81 | TDP1 (0.61) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL23620881 | 0.80 | L3MBTL1 (0.51) | TDP1MMP8L3MBTL1MAPK1TSHR | |
| SCHEMBL20180712 | 0.80 | L3MBTL1 (0.51) | TDP1MMP8L3MBTL1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196262-A1 | PREPARATION METHOD FOR HEXAHYDROFURO-FURAN-OL DERIVATIVE, AND INTERMEDIATE OF DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏瑞科医药科技有限公司 | 2019-10-17 | — | — | WO | disclosed |