Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290478 | 0.74 | KDM4E (0.47) | SMN1; SMN2POLBKDM4EMAPTKMT2A | |
| SCHEMBL279780 | 0.73 | KDM4E (0.49) | SMN1; SMN2POLBKDM4EMAPTKMT2A | |
| SCHEMBL12701157 | 0.73 | KDM4E (0.46) | SMN1; SMN2POLBKDM4EMAPTKMT2A | |
| SCHEMBL20338996 | 0.72 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBKMT2ACYP4F2CYP4A11 | |
| SCHEMBL30856559 | 0.72 | PIN1 (0.46) | SMN1; SMN2POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL2405898 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2POLBMAPTKMT2ACYP4F2 | |
| SCHEMBL11171940 | 0.71 | PIN1 (0.49) | SMN1; SMN2POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL8993937 | 0.71 | SMN1; SMN2 (0.63) | SMN1; SMN2POLBCYP4F2CYP4A11ALOX5 | |
| SCHEMBL6495234 | 0.70 | PIN1 (0.47) | SMN1; SMN2POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL6495233 | 0.70 | PIN1 (0.47) | SMN1; SMN2POLBMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196262-A1 | PREPARATION METHOD FOR HEXAHYDROFURO-FURAN-OL DERIVATIVE, AND INTERMEDIATE OF DERIVATIVE AND PREPARATION METHOD THEREFOR | 江苏瑞科医药科技有限公司 | 2019-10-17 | — | — | WO | disclosed |