Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22907349 | 0.87 | MEN1 (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL21120299 | 0.87 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL18646461 | 0.83 | KMT2A (0.38) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19318311 | 0.82 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL13296164 | 0.80 | APP (0.41) | KMT2AMEN1RIPK1ALDH1A1 | |
| SCHEMBL12733146 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1L3MBTL1MAPTRAB9A | |
| SCHEMBL2742136 | 0.80 | MEN1 (0.50) | KMT2AMEN1ALDH1A1LMNACA1 | |
| SCHEMBL12116550 | 0.79 | HPGD (0.46) | MAPTGAARAB9AALDH1A1CA1 | |
| SCHEMBL10159813 | 0.79 | PPARG (0.44) | KMT2AMEN1SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL23899582 | 0.78 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197506-A9 | AXL-SPECIFIC ANTIBODIES FOR CANCER TREATMENT | GENMAB A/S (DK) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019197506-A1 | AXL-SPECIFIC ANTIBODIES FOR CANCER TREATMENT | GENMAB A/S (DK) | 2019-10-17 | — | — | WO | disclosed |