Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23106667 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL19038332 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL19038333 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL21322473 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL16847757 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL22461613 | 0.74 | HTT (0.51) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL19038331 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL5697933 | 0.73 | PTGS1 (0.61) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL8763346 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 | |
| SCHEMBL23615406 | 0.73 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197506-A9 | AXL-SPECIFIC ANTIBODIES FOR CANCER TREATMENT | GENMAB A/S (DK) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019197506-A1 | AXL-SPECIFIC ANTIBODIES FOR CANCER TREATMENT | GENMAB A/S (DK) | 2019-10-17 | — | — | WO | disclosed |