Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19038332 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL19038331 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL22644546 | 0.87 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL23106667 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL23615406 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL21480710 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL14962675 | 0.79 | PTGS1 (0.61) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL21322473 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL16847757 | 0.78 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDHTTALDH1A1MAPT | |
| SCHEMBL14962678 | 0.77 | PTGS1 (0.64) | SMN1; SMN2HPGDHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158166-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | SUTURA THERAPEUTICS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
| US-20230158166-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | SUTURA THERAPEUTICS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
| US-11541124-B2 | Biologically active compound conjugated to a stapled or stitched peptide | SUTURA THERAPEUTICS LTD (TC) | 2023-01-03 | — | — | US | disclosed |
| US-20220062431-A1 | COMPOUNDS COMPRISING STAPLED OR STITCHED PEPTIDES FOR IMPROVED DRUG DELIVERY | SUTURA THERAPEUTICS LTD (GB) | 2022-03-03 | — | — | US | disclosed |
| US-20200353092-A1 | BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE | SUTURA THERAPEUTICS LTD (TC) | 2020-11-12 | — | — | US | disclosed |
| WO-2019002875-A1 | COMPOUNDS COMPRISING STAPLED OR STITCHED PEPTIDES FOR IMPROVED DRUG DELIVERY | SUTURA THERAPEUTICS LTD (TC) | 2019-01-03 | — | — | WO | disclosed |
| WO-2017109494-A1 | BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE | SUTURA THERAPEUTICS LTD (TC) | 2017-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541124-B2 | Biologically active compound conjugated to a stapled or stitched peptide | BPGM, TMPO, SLC7A1 | SMN1; SMN2 473/4885HPGD 4859/4885HTT 2697/4885 |
| US-20200353092-A1 | BIOLOGICALLY ACTIVE COMPOUND CONJUGATED TO A STAPLED OR STITCHED PEPTIDE | BPGM, TMPO, SLC7A1 | SMN1; SMN2 469/4885HPGD 4859/4885HTT 2695/4885 |
| US-20230158166-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | BPGM, PICALM, TMPO | SMN1; SMN2 623/4885HPGD 4874/4885HTT 3155/4885 |
| US-20220062431-A1 | COMPOUNDS COMPRISING STAPLED OR STITCHED PEPTIDES FOR IMPROVED DRUG DELIVERY | SPG11, SSBP1, SCAMP2 | SMN1; SMN2 943/4885HPGD 2779/4885HTT 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.