Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626980 | 0.85 | FAAH (0.41) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL21322473 | 0.80 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL16847757 | 0.80 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL24829524 | 0.80 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL17636179 | 0.80 | CYP19A1 (0.42) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL16274103 | 0.79 | MGLL (0.65) | HTTSMN1; SMN2HPGDFAAHMGLL | |
| SCHEMBL5970073 | 0.79 | MGLL (0.68) | FAAHMGLLPOLBKMT2AMEN1 | |
| SCHEMBL7035034 | 0.79 | MGLL (0.68) | FAAHMGLLPOLBKMT2AMEN1 | |
| SCHEMBL735230 | 0.79 | MGLL (0.68) | FAAHMGLLPOLBKMT2AMEN1 | |
| SCHEMBL40386 | 0.79 | MGLL (0.68) | FAAHMGLLPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191369-A1 | PROCESS FOR PREPARING EXTRACELLULAR VESICLES | CODIAK BIOSCIENCES, INC. (US) | 2020-09-24 | — | — | WO | disclosed |