Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23291367 | 0.68 | POLB (0.37) | — | |
| SCHEMBL1616764 | 0.63 | SLC18A3 (0.33) | — | |
| SCHEMBL23829580 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL1617127 | 0.61 | ALDH1A1 (0.32) | — | |
| SCHEMBL10379765 | 0.60 | — | — | |
| SCHEMBL9821429 | 0.59 | GABRR1 (0.33) | — | |
| SCHEMBL2148090 | 0.57 | ALDH1A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL6607826 | 0.56 | ALDH1A1 (0.40) | — | |
| SCHEMBL6829519 | 0.56 | ACE (0.33) | — | |
| SCHEMBL23465218 | 0.56 | TDP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011090935-A1 | PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-28 | — | — | WO | disclosed |
| EP-1610789-A4 | BICYCLIC PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO INC (US) | 2008-02-27 | — | — | EP | disclosed |
| EP-1610789-A1 | BICYCLIC PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | Merck & Co., Inc. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087159-A1 | BICYCLIC PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2004-10-14 | — | — | WO | disclosed |