Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17338875 | 0.58 | — | — | |
| SCHEMBL18375146 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL31056967 | 0.57 | MEN1 (0.35) | TDP1MEN1KMT2A | |
| SCHEMBL31731930 | 0.57 | ALDH1A1 (0.34) | POLBTDP1MEN1KMT2A | |
| SCHEMBL1616764 | 0.56 | SLC18A3 (0.33) | POLB | |
| Methane SCHEMBL15741155 | 0.56 | — | — | |
| SCHEMBL21359840 | 0.55 | ACE (0.37) | — | |
| SCHEMBL31474411 | 0.55 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL25371539 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL1617127 | 0.55 | ALDH1A1 (0.32) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814338-A1 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | Proteostasis Therapeutics, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |