Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.58 |
| ▸ | CARM1 | Q86X55 | 7/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21482272 | 0.92 | CARM1 (0.61) | PIK3CACARM1 | |
| SCHEMBL21486201 | 0.86 | PIK3CA (0.55) | PIK3CACARM1MTORPIK3R1 | |
| SCHEMBL21482287 | 0.83 | CARM1 (0.75) | CARM1 | |
| SCHEMBL21482273 | 0.81 | CARM1 (0.61) | PIK3CACARM1MTORPIK3R1 | |
| SCHEMBL21482282 | 0.81 | PIK3CA (0.57) | PIK3CACARM1MTORPIK3R1 | |
| SCHEMBL21482280 | 0.80 | CARM1 (0.62) | PIK3CACARM1MTORPIK3R1 | |
| SCHEMBL1311669 | 0.79 | PIK3CA (0.82) | PIK3CAMTORPIK3R1 | |
| SCHEMBL21462150 | 0.79 | PIK3CB (0.67) | PIK3CAMTORPIK3R1 | |
| SCHEMBL21482265 | 0.79 | PIK3CA (0.60) | PIK3CACARM1MTORPIK3R1 | |
| SCHEMBL1311223 | 0.79 | PIK3CA (0.77) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019196720-A1 | ARGININE METHYLTRANSFERASE INHIBITOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2019-10-17 | — | — | WO | disclosed |