SCHEMBL2148302

SCHEMBL2148302

O=C(O)C/C=C/c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 2/20 1.00
MAOB P27338 5/20 0.61
ALDH1A1 P00352 3/20 0.52
HDAC1 Q13547 3/20 0.52
CYP2D6 P10635 2/20 0.52
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
PLIN1 O60240 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
RECQL P46063 2/20 0.52
PLIN5 Q00G26 2/20 0.52
ABHD5 Q8WTS1 2/20 0.52
TNKS O95271 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC10 Q969S8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL582727 1.00 PAM (1.00) PAMMAOBALDH1A1HDAC1CYP2D6
SCHEMBL156767 1.00 PAM (1.00) PAMMAOBALDH1A1HDAC1CYP2D6
Ammonia Solution, Strong SCHEMBL6327618 0.98 PAM (0.96) PAMMAOBALDH1A1HDAC1CYP2D6
SCHEMBL387249 0.98 PAM (0.96) PAMMAOBALDH1A1HDAC1CYP2D6
Hydrochloric Acid SCHEMBL28759894 0.98 PAM (0.96) PAMMAOBALDH1A1HDAC1CYP2D6
Ammonia Solution, Strong SCHEMBL6327623 0.98 PAM (0.96) PAMMAOBALDH1A1HDAC1CYP2D6
Hydroxyamine SCHEMBL30636634 0.96 PAM (0.92) PAMMAOBALDH1A1HDAC1CYP2D6
Hydrazine SCHEMBL29236551 0.96 PAM (0.92) PAMMAOBALDH1A1HDAC1CYP2D6
Acetic Acid SCHEMBL30574222 0.94 PAM (0.88) PAMMAOBALDH1A1HDAC1CYP2D6
Butadiene SCHEMBL27795141 0.92 PAM (0.85) PAMMAOBALDH1A1HDAC1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-118894707-B Novel gypsum-based slurry composite rock wool clean board core material and preparation method thereof 山东汉诺宝嘉新材料科技有限公司 2025-04-25 CN claimed
CN-118894707-A Novel gypsum-based slurry composite rock wool clean board core material and preparation method thereof 山东汉诺宝嘉新材料科技有限公司 2024-11-05 CN claimed
CN-118530518-A Acid-alkali corrosion-resistant environment-friendly high-molecular pressure difference activated sealant 古莱特科技股份有限公司 2024-08-23 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-114108337-B Stripping cationic auxiliary agent and preparation method thereof 浙江震东新材料有限公司 2024-01-26 CN claimed
CN-109721467-B Process for preparing halohydrins 中国石油化工股份有限公司 2022-03-11 CN claimed
CN-114108337-A Cationic stripping auxiliary agent and preparation method thereof 浙江震东新材料有限公司 2022-03-01 CN claimed
CN-108658713-B Process for preparing beta-halohydrins 中国石油化工股份有限公司 2022-02-08 CN claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
EP-1585749-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2005-10-19 EP claimed
WO-2004063198-A1 DIAZEPINOINDOLE DERIVATIVES AS KINASE INHIBITORS PFIZER INC. (US) 2004-07-29 WO claimed
WO-1997048279-A1 AGENTS WITH ANTIFUNGAL ACTIVITY AND METHODS OF USE THEREOF UNIVERSITY OF ALBERTA (US) 1997-12-24 WO claimed
US-5607953-A ANTIISCHEMIC AGENTS EISAI CO., LTD. (JP) 1997-03-04 US claimed
EP-0344577-B1 Butenoic or propenoic acid derivatives EISAI CO LTD (JP) 1996-10-09 EP claimed
US-5177089-A Antiischemic agent, vasodilator EISAI CO., LTD. (JP) 1993-01-05 US claimed
US-5047417-A Butenoic or propenoic acid derivatives EISAI CO. LTD. (JP) 1991-09-10 US claimed
CN-1040366-A Butenoic acid or acrylic acid derivative EISAI CO LTD (JP) 1990-03-14 CN claimed
EP-0344577-A2 Butenoic or propenoic acid derivatives Eisai Co., Ltd. (JP) 1989-12-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 PAM 2345/4885MAOB 62/4885ALDH1A1 1569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.