SCHEMBL21483088

SCHEMBL21483088

OC[C@H]1CNCCC1(F)F

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ARG1 P05089 2/20 0.35
▸ ARG2 P78540 2/20 0.35
▸ SYK P43405 2/20 0.30
▸ KCNH2 Q12809 2/20 0.30
▸ AURKB Q96GD4 2/20 0.30
▸ APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21462466 1.00 ARG1 (0.35) ARG1ARG2SYKKCNH2AURKB
SCHEMBL12527141 1.00 ARG1 (0.35) ARG1ARG2SYKKCNH2AURKB
Hydrochloric Acid SCHEMBL2345098 0.98 ARG1 (0.34) ARG1ARG2SYKKCNH2AURKB
SCHEMBL12526115 0.78 SYK (0.33) ARG1ARG2SYKKCNH2AURKB
SCHEMBL25729346 0.77 — —
SCHEMBL29565061 0.76 ARG1 (0.38) ARG1ARG2SYKKCNH2AURKB
Hydrochloric Acid SCHEMBL25272059 0.76 APLNR (0.31) APLNR
SCHEMBL28411820 0.74 SYK (0.38) SYKKCNH2AURKB
SCHEMBL18647890 0.74 SYK (0.31) SYKKCNH2AURKB
SCHEMBL22756590 0.72 ARG1 (0.32) ARG1ARG2SYKKCNH2AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 — — EP disclosed
US-20260042776-A1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2026-02-12 — — US disclosed
US-12486285-B2 BCL6 inhibitors CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2025-12-02 — — US disclosed
CN-112334475-B BCL6 inhibitors 癌症研究技术有限公司 2024-10-29 — — CN disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 — — US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 — — US disclosed
US-20230287003-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2023-09-14 — — US disclosed
EP-4201939-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2023-06-28 — — EP disclosed
EP-4201939-A1 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2023-06-28 — — EP disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 — — EP disclosed
EP-3774817-B1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2022-12-07 — — EP disclosed
US-11512095-B2 BCL6 inhibitors THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2022-11-29 — — US disclosed
US-20210163497-A1 BCL6 INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-06-03 — — US disclosed
US-20210163497-A1 BCL6 INHIBITORS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2021-06-03 — — US disclosed
CN-112334475-A BCL6 inhibitor 癌症研究技术有限公司 2021-02-05 — — CN disclosed
WO-2019197842-A1 BCL6 INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2019-10-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163497-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 ARG1 2862/4885ARG2 4079/4885SYK 970/4885
US-20230287003-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL3 ARG1 2862/4885ARG2 4079/4885SYK 970/4885
US-12486285-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 ARG1 2862/4885ARG2 4079/4885SYK 970/4885
US-11512095-B2 BCL6 inhibitors BCL6, BCL6B, BCL3 ARG1 2862/4885ARG2 4079/4885SYK 970/4885
US-20260042776-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL9 ARG1 1337/4885ARG2 3437/4885SYK 243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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