⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807518 | 0.84 | — | — | |
| SCHEMBL20393788 | 0.75 | GPR52 (0.30) | — | |
| SCHEMBL24809381 | 0.67 | — | — | |
| SCHEMBL23020014 | 0.65 | MME (0.32) | — | |
| SCHEMBL12810474 | 0.64 | — | — | |
| SCHEMBL11573093 | 0.64 | ATM (0.34) | — | |
| SCHEMBL18848867 | 0.63 | AKT1 (0.32) | — | |
| SCHEMBL23543675 | 0.63 | ALDH1A1 (0.41) | — | |
| SCHEMBL21082634 | 0.62 | AKT1 (0.34) | — | |
| SCHEMBL24895937 | 0.62 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11253536-B2 | Methods for directed folding assembly or dimerization of proteins by templated assembly reactions | TRIBIOTICA LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20190314397-A1 | Methods For Directed Folding Assembly Or Dimerization Of Proteins By Templated Assembly Reactions | TRIBIOTICA LLC | 2019-10-17 | — | — | US | disclosed |