Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 15/20 | 0.74 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17256336 | 0.85 | ASGR1 (1.00) | ASGR1HPSE | |
| SCHEMBL23346073 | 0.73 | ASGR1 (0.62) | ASGR1 | |
| SCHEMBL25084266 | 0.73 | ASGR1 (0.72) | ASGR1 | |
| SCHEMBL17256358 | 0.71 | ASGR1 (1.00) | ASGR1 | |
| SCHEMBL26888865 | 0.69 | ASGR1 (0.64) | ASGR1HPSE | |
| SCHEMBL26698324 | 0.69 | ASGR1 (0.64) | ASGR1HPSE | |
| SCHEMBL25867163 | 0.69 | ASGR1 (0.64) | ASGR1HPSE | |
| SCHEMBL26879913 | 0.69 | ASGR1 (0.65) | ASGR1 | |
| SCHEMBL24256177 | 0.69 | ASGR1 (0.65) | ASGR1 | |
| SCHEMBL26879886 | 0.68 | ASGR1 (0.60) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199634-A1 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | YALE UNIVERSITY (US) | 2019-10-17 | — | — | WO | disclosed |