SCHEMBL21484780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21484811	0.90	MRE11 (0.52)	MRE11CSNK2A1CSNK2A2CSNK2BCSNK2A3
	SCHEMBL21484641	0.88	MRE11 (0.62)	MRE11CSNK2A1CSNK2A2CSNK2BCSNK2A3
	SCHEMBL21484751	0.88	MRE11 (0.51)	MRE11MGAMGAASIMGAM2
	SCHEMBL21484735	0.87	LMNA (0.48)	MRE11MGAMGAASIMGAM2
	SCHEMBL21484750	0.85	MRE11 (0.60)	MRE11CSNK2A1CSNK2A2CSNK2BCSNK2A3
	SCHEMBL21484858	0.82	MRE11 (0.50)	MRE11MGAMGAASIMGAM2
	SCHEMBL21484670	0.79	MRE11 (0.61)	MRE11GAAEGFRLMNAMAPT
	SCHEMBL21484671	0.79	MRE11 (0.60)	MRE11CSNK2A1EGFRLMNAMAPT
	SCHEMBL21484777	0.78	MRE11 (0.51)	MRE11CSNK2A1CSNK2A2CSNK2BCSNK2A3
	SCHEMBL21484857	0.78	MRE11 (0.51)	MRE11MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.