Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127045 | 0.87 | TSHR (0.68) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL20567847 | 0.86 | TSHR (0.56) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1126753 | 0.86 | TSHR (0.53) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL19663897 | 0.81 | GRIA4 (0.61) | TSHRKMT2ASMN1; SMN2LMNAUSP2 | |
| SCHEMBL28645817 | 0.80 | TSHR (0.54) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL4378375 | 0.80 | GRIA4 (0.73) | TSHRALDH1A1NPSR1KDM4E | |
| SCHEMBL1381652 | 0.79 | TSHR (0.55) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1127080 | 0.79 | TSHR (0.55) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL8785961 | 0.79 | TSHR (0.55) | TSHRKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1126966 | 0.77 | TSHR (0.53) | TSHRKMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596150-B2 | Antifungal agents | F2G LIMITED (GB) | 2020-03-24 | — | — | US | disclosed |
| US-20190314333-A1 | ANTIFUNGAL AGENTS | F2G LTD (GB) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314333-A1 | ANTIFUNGAL AGENTS | DPM1, AADAC, PIK3C3 | TSHR 4627/4885KMT2A 777/4885MAPT 3096/4885 |
| US-10596150-B2 | Antifungal agents | DPM1, AADAC, PIK3C3 | TSHR 4627/4885KMT2A 777/4885MAPT 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.