Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1625456 | 0.98 | NOS1 (0.56) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL6935851 | 0.94 | MAPT (0.57) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL17186436 | 0.92 | MAPT (0.55) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL6198752 | 0.92 | MAPT (0.60) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13819007 | 0.89 | NOS1 (0.46) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL1891210 | 0.86 | NOS1 (0.57) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8781018 | 0.85 | NOS1 (0.59) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL2338709 | 0.84 | NOS1 (0.55) | NOS1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL12376924 | 0.84 | NOS1 (0.43) | NOS1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL12597686 | 0.82 | HDAC1 (0.61) | NOS1HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707868-A | Benzimidazole substituted halogenated phenyl n-butylamidine-based compound and preparation method thereof | 山东福长药业有限公司 | 2021-04-27 | — | — | CN | disclosed |
| WO-2019197015-A1 | COMPOSITION COMPRISING 4-PHENYLBUTYRIC ACID DERIVATIVES & OPIOIDS | TRUOG PETER (CH) | 2019-10-17 | — | — | WO | disclosed |
| US-9109048-B2 | Inhibition of tumor growth | LYTIX BIOPHARMA AS (NO) | 2015-08-18 | — | — | US | disclosed |
| US-20140037657-A1 | INHIBITION OF TUMOR GROWTH | LYTIX BIOPHARMA AS (NO) | 2014-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140037657-A1 | INHIBITION OF TUMOR GROWTH | STING1, VIP, MIF | NOS1 493/4885HDAC1 2445/4885HDAC3 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.